
WHAT IS FRAMELESS STEREOTACTIC RADIOSURGERY (SRS)
Stereotactic Radiosurgery (SRS) is a well established non-invasive alternative to traditional surgery that delivers highly focused radiation to treat brain and spine tumors without incisions, scalpels, or hospital stays. Despite its name, no surgery is involved — instead, multiple beams of radiation are precisely directed at the target with sub-millimetre accuracy, destroying cancer cells while preserving surrounding healthy tissue. With the use of advanced image guidance technology, the patient no longer requires a rigid metal frame screwed into his skull during treatment.
This safe and effective approach allows patients to return to normal life quickly, with minimal disruption.
CONDITIONS TREATED WITH SRS

BRAIN
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Benign Brain Tumors
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Meningioma
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Pituitary tumours
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Acoustic neuroma (vestibular schwannoma)
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Malignant Brain Tumors
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Brain metastases
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GBM (Glioblastoma Multiforme) recurrence
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Chordoma
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Chondrosarcoma
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Others
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Vascular malformations (AVM, cavernomas)
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Functional disorders such as trigeminal neuralgia
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SPINE
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Spine metastases
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Benign and malignant spinal tumours
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Selected vascular abnormalities
HOW FRAMELESS STEREOTACTIC RADIOSURGERY WORKS

PLANNING PART 1
Same day or next day CT simulation will be arranged for our patients. Our radiation therapists will use CT scans to map the exact shape, size, and position of the treatment target. All patients will be fitted with an individualised thermoplastic mask for treatment accuracy.

PLANNING PART 2
Our specialist oncologist will use his expertise to interpret the images and defining the precise treatment area, ensuring only the cancer is targeted. Equal care is taken to define all the organs at risk so that the radiation fields can be bent around them.

PLANNING PART 3
Using advanced software, our radiation oncologist and medical physicist will calculate the safest and most effective way to deliver radiation beams. Their clinical experience ensures the optimal balance between destroying cancer cells and protecting surrounding healthy tissue.

QUALITATIVE ANALYSIS
Our radiation therapists would run quality assurance tests on the machines daily to check that the settings are correct to ensure optimal delivery and accuracy.

PRECISION TARGETING
Patients will lie comfortably on the treatment couch while multiple beams of radiation are directed from different angles, converging precisely on the lesion. The care team continuously monitors positioning to maintain sub-millimetre accuracy.

AFTERCARE
Because SRS is non-invasive, there are no incisions or stitches. Most patients go home the same day. Your doctor will review your progress, schedule follow-up imaging, and provide ongoing support to ensure the best outcome.
FRAME BASED RADIOSURGERY VS FRAMELESS RADIOSURGERY
Radiosurgery or SRS can be delivered using either a frame-based system, such as Gamma Knife, or modern image-guided frameless systems using advanced Linear Accelerators. While both are highly accurate, frame-based approaches require a rigid head frame fixed to the skull with metal screws, which are uncomfortable and invasive. Frameless radiosurgery achieves the same sub-millimetre precision using image-guided tracking and a simple custom mask — offering patients a safe, non-invasive, and far more comfortable experience, without compromising on outcomes.
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IMMOBILISATION
Rigid metal frame with metal screws fixed to the skull
COMFORT
Uncomfortable, requires invasive fixation
SCOPE
Limited to brain conditions only
SESSIONS
Typically single-session treatment
ACCURACY
Sub-millimetre precision via rigid frame fixation
TOTAL DURATION
15 mins to few hours of radiation + unscrewing of frame after
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IMMOBILISATION
Uses a thermoplastic mask or soft headrest
COMFORT
Non-invasive and more comfortable for patients
SCOPE
Can treat both brain and spine (and some other sites)
SESSIONS
Flexible — single or multiple sessions (fractions)
ACCURACY
Sub-millimeter precision via advanced image-guided tracking
TOTAL DURATION
15 - 45 minutes only

QUICK TREATMENT TIME
1 - 5 sessions

NO OPEN SURGERY
No cuts or stitches. Bloodless.
No operation risks.

OUTPATIENT BASED
No hospital stay required

NO ANAESTHESIA
Comfortable and painless
Speak with Our Brain and Spine Specialist Oncologist Today

DR. DANIEL TAN YAT HARN (PBM)
Director, Senior Consultant Radiation Oncologist
MBBS (SIN), FRCR (Clinical Oncology, UK), FAMS (Radiation Oncology)
MBA (Healthcare Management)
Dr. Daniel Tan is Medical Director and Senior Consultant Radiation Oncologist at Centre for Stereotactic Radiosurgery (CSR), bringing with him over 20 years of experience in cancer care. Previously a Consultant Radiation Oncologist at the National Cancer Centre Singapore (NCCS), he was instrumental in developing the region’s first advanced Spine, Prostate, and Liver SRS/SBRT programs, pioneering their introduction in Southeast Asia. Dr Daniel’s radiosurgery expertise extends beyond the shores of Singapore. In June 2024, Dr Daniel was elected to the Board of Directors of the International Stereotactic Radiosurgery Society (ISRS), the world’s largest radiosurgery professional organisation.
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